Some Cancer Risks Lessen when Asbestos Exposure Ends
Monday, April 7th, 2008A recent study conducted among Italian asbestos cement workers demonstrates that the risk of lung cancer in people exposed to asbestos falls after exposure to the toxic substance ends.
A total of 3,434 individuals, both men and women, were involved in the study. All had worked at an asbestos cement plant and all were working at the plant in 1950 or had been hired between 1950 and 1986, when the plant halted production.
Both men and women in the group were at increased risk of dying from any cause, any type of cancer, lung cancer, and pleural and peritoneal mesothelioma, the researchers found. The women carried a higher risk of developing ovarian and uterine cancer. Other cancers that the researchers thought might be found at a higher rate among these workers were not any different than in the general population. Particularly, the researchers studied the incidence of esophageal and laryngeal cancer but found no marked difference.
The risk of lung cancer was highest for men 30 to 39 years after the end of exposure, and for women in the 20 to 29 years after exposure ended, and then began to decline, the study notes. However, the risk for peritoneal mesothelioma continued to rise even 40 years after exposure had ended.
These findings, note Magnani and colleagues, suggest that there may be different mechanisms by which asbestos exposure causes mesothelioma in the pleura and the peritoneum.





